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System One Scientist IV in Ridgefield, Connecticut

Job Title: Scientist IV

Location: Ridgefield, CT

Type: contract

Overview

Join one of the worlds largest pharmaceutical driven by science and seek to push the boundaries of what's possible in medicine and explore new options in life-enhancing treatments.

Responsibilities

  • Design/develop/perform various functional genomics assays, such as CRISPR pool screening, bulk RNA-seq, single cell–seq, spatial transcriptomics, CITE-seq, WES, Perturb-seq and 10X Multiome on tissue, cell or nuclei suspensions;

  • Assist with technical guidance and training, as appropriate, to Research scientists a) in FGSL technologies and techniques and b) to conduct assays, troubleshoot and solve technical issues;

  • Serve as scientific monitor for assay performance and project management at external CROs;

  • Documents and maintains detailed laboratory records in accordance with SOP's and policies;

  • Operates and maintains lab equipment in collaboration with other lab members;

  • Assists with budget preparation and acquisition of necessary supplies and equipment;

  • Defines and performs appropriate QC measures;

  • Follows relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field;

  • Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation;

  • Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports

  • Automate processing and results reporting and delivery;

  • Reports and treats data with a high level of integrity and ethics.

    Requirements

    Requirements

  • Demonstrated experience with CRISPR assays

  • Demonstrated experience with next-generation sequencing (NGS) and functional genomics, single cell technologies;

  • Proficient in cell culture.

  • Experience in automation and software programing is a plus;

  • Able to perform variety of FGS experimental techniques at the same time;

  • Demonstrated experience working in a multi-disciplinary and collaborative environment;

  • Ability to troubleshoot FGS experiments both individually and as part of a team.

  • Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner.

    Education:

  • Ph.D. or Master’s degree from an accredited institution with 6+ years of experience in molecular, cell biology, or related scientific discipline.

    Benefits

    System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.

    #M3

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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