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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

The Peptide Therapeutics group at Lilly is seeking to recruit a full-time Associate Synthetic Chemist. The successful applicant will be an enthusiastic and highly motivated team player who will make significant contributions to preclinical drug discovery and development efforts. This is an exciting opportunity to join a multidisciplinary team of researchers working to develop the next generation of peptide-related biotherapeutics across a range of therapeutic areas. Creative, enthusiastic, and highly motivated synthetic chemists with limited peptide chemistry experience and deeper expertise in the areas of small molecules, oligonucleotides, or protein conjugation are welcome to apply.

Responsibilities:

The successful candidate will:

• Utilize state-of-the-art synthesis techniques to drive compound generation.

• Synthesize target molecules, perform purification and QC analysis, propose alternative synthetic strategies, and overcome synthetic challenges.

• Analyze and interpret structure-activity relationships to make design recommendations to drive projects forward.

• Collaborate with fellow chemists and scientists from other disciplines and drug modalities in a team environment that is focused on achieving success.

• Search relevant chemical and scientific literature with limited supervision.

• Accurately document experimental procedures and communicate results via verbal presentations and written reports.

Basic Requirements:

• B.S. in Chemistry or a related field with at least 2 years of industry experience OR M.S. in Chemistry or a related field with experience.

Additional Skills/Preferences:

• A comprehensive understanding of synthetic peptide chemistry and/or organic chemistry is critical.

• Experience with synthesis, characterization, and optimization of macrocyclic peptides is preferable.

• Experience with peptide synthesis instrumentation, purification, and analysis by HPLC and mass spectrometry is desirable but not necessary. Skilled synthetic organic chemists with a desire to transition to the area of peptide therapeutics are encouraged to apply.

• Experience in the bioconjugation of fluorescent labels, carbohydrates, oligonucleotides, small molecules and/or proteins to synthetic peptides or other modalities is valuable.

• Experience in structure-based drug design using computational methods is beneficial.

• The successful candidate will have superb communication and organizational and interpersonal skills and will excel working as part of diverse cross-functional teams.

• Essential traits include a desire to present their work and understand its impact on drug discovery efforts, and an eagerness to take on diverse scientific and technical challenges as they arise.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( LillyRecruitingCompliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

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Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

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